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🧬 Elevate your mental edge with science-backed methylation mastery!
MethylPro Cofactors with 15 mg L-Methylfolate is a professional-strength, hypoallergenic supplement designed to support methylation pathways, mood, and neurotransmitter balance. Fortified with active vitamin B6, B12, and magnesium, it promotes brain health and biochemical reactions while being free from common allergens. Trusted for over 45 years, this clean formula is ideal for adults seeking focused mental clarity and emotional balance.








| ASIN | B0731V1VXX |
| Age Range Description | Adult |
| Allergen Information | Dairy Free, Egg Free, Gluten Free, Soy Free |
| Best Sellers Rank | #59,761 in Health & Household ( See Top 100 in Health & Household ) #1,096 in Magnesium Mineral Supplements |
| Brand | MethylPro |
| Brand Name | MethylPro |
| Customer Reviews | 4.3 out of 5 stars 142 Reviews |
| Diet Type | Gluten Free, Vegetarian |
| Dosage Form | Capsule |
| Flavor | Unflavored |
| Global Trade Identification Number | 00838287008033 |
| Item Dimensions | 3.8 x 2 x 2 inches |
| Item Form | Capsule |
| Item Highlight | Vitamins B6, B12 and Magnesium with Active Folate for Methylation and Biochemical Reactions, Hypoallergenic |
| Item Weight | 5.28 ounces |
| Manufacturer | MethylPro |
| Manufacturer Part Number | Methyl-803-Quatrefolic15mgPlusCofactors |
| Material Type Free | Dairy Free, Egg Free, Magnesium Stearate Free, Soy Free, Tree Nuts Free |
| Model Number | Methyl-803-Quatrefolic15mgPlusCofactors |
| Number of Items | 1 |
| Primary Supplement Type | Vitamin B-6 15 mg (as 25 mg Pyridoxal 5' Phosphate) Folate 25 mg DFE (15 mg from L-5-Methylfolate, calcium salt) Vitamin B-12 1000 mcg (as Methylcobalamin) Magnesium 125 mg (as Magnesium Citrate) Primary Supplement Type Vitamin B-6 15 mg (as 25 mg Pyridoxal 5' Phosphate) Folate 25 mg DFE (15 mg from L-5-Methylfolate, calcium salt) Vitamin B-12 1000 mcg (as Methylcobalamin) Magnesium 125 mg (as Magnesium Citrate) See more |
| Product Benefits | Brain Health Support |
| Specific Uses For Product | Indoor |
| UPC | 838287008033 |
| Unit Count | 30 Count |
T**N
Great Product and Brand
My Dr. suggested these for me as I had a genetic testing done and come to find out I have a folic acid issue. Great product and I'm still taking them months later. They do help! I would check with your Dr. before taking to be on the safe side.
M**K
As described, easy to start—still early for results
I decided to try this after my GeneSight testing showed an MTHFR gene mutation, and I wanted a methylated form of folate instead of standard folic acid. This formula checked the boxes for me with L-methylfolate plus B6, B12, and magnesium, so it seemed like a straightforward place to start. So far, it’s been easy to incorporate into my routine—just one capsule a day. The capsules are a normal size and easy to swallow, and I haven’t noticed any unpleasant taste or aftereffects. It arrived exactly as described, sealed properly, and with a reasonable expiration date. It’s still too early to comment on any real changes in mood or energy, which is something I expected going in since these types of supplements can take time. I also started with the full 15 mg dose but plan to pay attention to how I feel and adjust if needed. Overall, no issues with quality and seems like a solid option if you’re specifically looking for a methylated folate supplement. The packaging did arrive looking a bit different than the photo listed on Amazon. Just keep expectations realistic on timing and consider checking with a healthcare provider if you’re new to this kind of supplementation.
M**L
Expensive but great product
Thank you for getting it to me so quickly. My doctor wants me to take this every day I think for the rest of my life. I just wish it wasn’t so expensive.
K**N
something changed
Something happened to this companies product. We bought it for years for my husbands genetic issue. All of a sudden the packaging changed, he started having mood issues, stomach problems and in general it is not working as it was. We are looking for other options for this.
I**E
MTHFR Gene Mutation
I am lacking the gene therefore I need L-methyl to help my body process the B vitamin and medicine alone. It has helped with depression and been a game changer for me. I started at 1mg and now take 15mg. The price went up recently as I think more are aware that they can get it without having to get the RX in which has all the added ingredients. #GoodStuff #iMMEURU
S**R
Help regulate bipolar illness
I use this supplement to help regulate bipolar illness. It is a cost-effective way to get methylfolate needed to do this.
K**J
Boosts effect of anti-depressants if tests show your DNA does not let the meds absorb readily.
This med combines with my anti/depressents and makes them more effective. It is quite expensive for a supplement that lasts one month.
A**L
Only brand I trust
I have an MTHFR gene mutation that caused my miscarriages, so I began taking this with doctor’s recommendation. My folate levels aren’t within a normal range since taking this product and my OB is confident that the next time I get pregnant this will be a huge factor in helping my little one survive. Amazing product.
Trustpilot
2 weeks ago
1 month ago