---
product_id: 530540970
title: "PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2"
brand: "apagard"
price: "B/.104"
currency: PAB
in_stock: true
category: "Apagard"
url: https://www.desertcart.com.pa/products/530540970-premio-sangis-nano-hydroxyapatite-toothpaste-for-naturally-whiter-teeth-no
store_origin: PA
region: Panama
---

# Fluoride-free natural formula Nano-Hydroxyapatite for enamel repair Double mint for lasting fresh breath PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2

**Brand:** apagard
**Price:** B/.104
**Availability:** ✅ In Stock

## Summary

> 🦷 Elevate your smile game with Japan’s secret to naturally radiant teeth!

## Quick Answers

- **What is this?** PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2 by apagard
- **How much does it cost?** B/.104 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.pa](https://www.desertcart.com.pa/products/530540970-premio-sangis-nano-hydroxyapatite-toothpaste-for-naturally-whiter-teeth-no)

## Best For

- apagard enthusiasts

## Why This Product

- Trusted apagard brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Triple Daily Defense:** Recommended 3x/day brushing to continuously remove plaque and enhance enamel strength.
- • **Long-Lasting Freshness:** Double mint flavor keeps your breath confidently fresh throughout your busy day.
- • **Fluoride-Free & Family Safe:** Gentle yet effective formula perfect for all ages, supporting healthy smiles without harsh chemicals.
- • **Trusted Japanese Innovation:** From Sangi Co., Ltd., a leader since the 1970s, now a top-rated choice in US oral care.
- • **Revolutionary Nano-Hydroxyapatite:** Repairs and whitens teeth naturally with Japan’s patented nano-mHAP technology.

## Overview

APAGARD® PREMIO is a fluoride-free, nano-hydroxyapatite toothpaste from Japan designed for natural enamel repair and whitening. Its patented nano-mHAP formula gently removes plaque, resists stains, and freshens breath with a refreshing double mint flavor. Ideal for family use, it supports daily oral health with a trusted, science-backed approach that’s been perfected since the 1970s.

## Description

Ingredients (INCI name): AQUA, DICALCIUM PHOSPHATE, GLYCERIN, HYDROXYAPATITE, SILICA, PEG-8, SODIUM LAURYL SULFATE, CELLULOSE GUM, AROMA, TRIMAGNESIUM PHOSPHATE, HYDROLYZED CONCHIOLIN PROTEIN, SODIUM SACCHARIN, GLYCYRRHETINIC ACID, CETYLPYRIDINIUM CHLORIDE, LAURYL IETHYLENEDIAMINOGLYCINE HCL

## Features

- APAGARD, Japan's leading toothpaste series for naturally beautiful teeth, is now available in the US. Discover the secret of naturally beautiful teeth from Japan. Contains Sangi's original nano-hydroxyaptite (nano-mHAP), almost the same substance as the hydroxyapatite that our teeth are made of, first synthesized in the 1970s by Sangi Co., Ltd
- APAGARD cleans the teeth and helps remove plaque with regular brushing.
- APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package, ideal for family use.
- For the best effect from nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/day is recommended) (3) Rinse lightly and spit out after brushing, so nano-mHAP remaining will enrich your saliva and continue its work.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0C379SKGN |
| ASIN  | B0C379SKGN |
| Age Range Description | Adult |
| Best Sellers Rank | #10,219 in Health & Household ( See Top 100 in Health & Household ) #202 in Toothpaste |
| Brand Name | APAGARD |
| Capacity | 3.7 ounces |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,450) |
| Date First Available  | April 23, 2023 |
| Flavor | Mint |
| Item Form | Paste |
| Item Weight | 0.14 Grams |
| Item model number  | 4987643122183 |
| Manufacturer | SANGI Co., Ltd. |
| Manufacturer  | SANGI Co., Ltd. |
| Manufacturer Part Number | 4987643122183 |
| Material Features | Natural |
| Material Type Free | Fluoride Free |
| Model Number | 4987643122183 |
| Number of Items | 1 |
| Package Quantity | 1 |
| Package Type Name | Tube |
| Product Benefits | Enhanced brightness, stain resistance, fresh breath, and hypersensitivity relief |
| Recommended Uses For Product | Cleaning |
| Target Audience | Unisex Adults |
| Unit Count | 3.53 Ounce |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** APAGARD
- **Flavor:** Mint
- **Item Form:** Paste
- **Material Type Free:** Fluoride Free

## Images

![PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2 - Image 1](https://m.media-amazon.com/images/I/61eDwvzPDGL.jpg)

## Questions & Answers

**Q: Complete list of ingredients?**
A: Google "Premio Apagard ingredients", it's in English on several websites. It's also in Japanese and English on the product box, just not on the tube itself.

**Q: Still flouride free?**
A: Fluoride is not listed as an ingredient on the outside of the box that the tube is shipped in. An additional label in English is pasted over the Japanese, I suppose for when the product is shipped to an English-speaking country.

**Q: Does this toothpaste have an expiration in storage?**
A: The shelf life of Apagard Premio toothpaste is two years.

**Q: What is the percentage of Nano Hydroxyapatite? And what is the flavor?**
A: Apagard uses 10% and 15%, depending on the toothpaste. But that's not total % of the toothpaste in the tube. That suspension is added to the toothpaste. Boka uses a 15.5% suspension, and the total amount is 2% of the toothpaste.  The flavor of the toothpaste is a very light mint.

## Frequently Bought Together

- APAGARD® PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2
- Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Refresh Mint Flavor, 4 Fl Oz 1Pk
- Apagard Tooth Polish Royal 135g toothpaste, Direct from Japan

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*Product available on Desertcart Panama*
*Store origin: PA*
*Last updated: 2026-08-01*