---
product_id: 539193876
title: "Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version"
brand: "apagard"
price: "B/.150"
currency: PAB
in_stock: true
reviews_count: 5
category: "Apagard"
url: https://www.desertcart.com.pa/products/539193876-apagard-premio-toothpaste-105g-3-7-oz-nano-hydroxyapatite-high
store_origin: PA
region: Panama
---

# Brightens teeth naturally without harsh chemicals Nano-hydroxyapatite remineralizes enamel Long-lasting 2-pack for daily family use Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version

**Brand:** apagard
**Price:** B/.150
**Availability:** ✅ In Stock

## Summary

> 🦷 Elevate your smile game with Japan’s secret to naturally brilliant teeth!

## Quick Answers

- **What is this?** Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version by apagard
- **How much does it cost?** B/.150 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.pa](https://www.desertcart.com.pa/products/539193876-apagard-premio-toothpaste-105g-3-7-oz-nano-hydroxyapatite-high)

## Best For

- apagard enthusiasts

## Why This Product

- Trusted apagard brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Family-Ready Value Pack:** Two generous 105g tubes designed for consistent use and lasting oral health benefits.
- • **Triple-Action Oral Care:** Simultaneously cleans plaque, controls stains, and freshens breath for all-day confidence.
- • **Trusted Japanese Innovation:** From the pioneers of hydroxyapatite toothpaste since the 1970s, now available in the US.
- • **Gentle Yet Powerful Whitening:** Achieve a natural, radiant smile without sensitivity or abrasive agents.
- • **Enamel-Boosting Nano Technology:** Harnesses Japan’s patented nano-mHAP to rebuild and strengthen your teeth from within.

## Overview

Premio Toothpaste features Sangi’s original nano-hydroxyapatite formula, scientifically designed to remineralize enamel, reduce plaque, and brighten teeth gently. This 2-pack offers a balanced, all-age oral care solution trusted in Japan since the 1970s, now optimized for daily use in the US market to deliver lasting freshness, stain control, and sensitivity prevention.

## Description

Ingredients (INCI name): AQUA, DICALCIUM PHOSPHATE, GLYCERIN, HYDROXYAPATITE, SILICA, PEG-8, SODIUM LAURYL SULFATE, CELLULOSE GUM, AROMA, TRIMAGNESIUM PHOSPHATE, HYDROLYZED CONCHIOLIN PROTEIN, SODIUM SACCHARIN, GLYCYRRHETINIC ACID, CETYLPYRIDINIUM CHLORIDE, LAURYL IETHYLENEDIAMINOGLYCINE HCL

Review: I read an article several years ago about hydroxyapatite toothpaste, and gave it a try. I will never go back, and have been so pleased with the appearance and feel of my teeth in my mouth. I have tried many different brands during this time, and this brand really stood out to me, with its pleasant taste, excellent cleaning, and great mouth feel. In all fairness, there are many other great brands available, which are also very good. Since finding this new type of toothpaste, I have to question why it is not available mainstream in the US, and advertised. My dentist asked me if I was using a teeth whitening product, and didn’t seem very welcoming, when I shared what I was using. This product, cleans, whitens, and works to prevent teeth sensitivity. Excellent product.
Review: アマゾンはいつも安くて助かっています。こちらを使い始めてからほんとにステインがつかなくなりました。歯と歯の間に少しついてしまうけど、ホワイトニングにそこまでこだわっていないので歯科検診時に取ってもらうことで良しとしています。 これまで知覚過敏対策の歯磨き粉ばかり使っていたけど、だんだん落ち着いてきたので今は専らアパガードです。プレミアムも買ってしまいました！

## Features

- APAGARD, Japan's leading toothpaste series for naturally beautiful teeth, is now available in the US. Discover the secret of naturally beautiful teeth from Japan. Contains Sangi's original nano-hydroxyaptite (nano-mHAP), almost the same substance as the hydroxyapatite that our teeth are made of, first synthesized in the 1970s by Sangi Co., Ltd
- APAGARD cleans the teeth and helps remove plaque with regular brushing.
- APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package, ideal for family use.
- For the best effect from nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/day is recommended) (3) Rinse lightly and spit out after brushing, so nano-mHAP remaining will enrich your saliva and continue its work.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0C379SKGN |
| ASIN  | B0C379SKGN |
| Age Range Description | Adult |
| Best Sellers Rank | #25,713 in Health ( See Top 100 in Health ) #782 in Toothpaste |
| Brand | APAGARD |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,160) |
| Customer reviews | 4.5 4.5 out of 5 stars (1,160) |
| Date First Available | 20 June 2023 |
| Format | Paste |
| Item model number  | 4987643122183 |
| Manufacturer  | SANGI Co., Ltd. |
| Package Dimensions  | 21.31 x 8.31 x 4.5 cm; 0.14 g |
| Units | 218.84 Milliliters |

## Product Details

- **Age range (description):** Adult
- **Brand:** APAGARD
- **Flavour:** Mint
- **Item form:** Paste
- **Material type free:** Fluoride Free

## Images

![Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version - Image 1](https://m.media-amazon.com/images/I/61eDwvzPDGL.jpg)

## Questions & Answers

**Q: Complete list of ingredients?**
A: Google "Premio Apagard ingredients", it's in English on several websites. It's also in Japanese and English on the product box, just not on the tube itself.

**Q: Still flouride free?**
A: Fluoride is not listed as an ingredient on the outside of the box that the tube is shipped in. An additional label in English is pasted over the Japanese, I suppose for when the product is shipped to an English-speaking country.

**Q: Does this toothpaste have an expiration in storage?**
A: The shelf life of Apagard Premio toothpaste is two years.

**Q: What is the percentage of Nano Hydroxyapatite? And what is the flavor?**
A: Apagard uses 10% and 15%, depending on the toothpaste. But that's not total % of the toothpaste in the tube. That suspension is added to the toothpaste. Boka uses a 15.5% suspension, and the total amount is 2% of the toothpaste.  The flavor of the toothpaste is a very light mint.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by W***S on 7 September 2025*

I read an article several years ago about hydroxyapatite toothpaste, and gave it a try. I will never go back, and have been so pleased with the appearance and feel of my teeth in my mouth. I have tried many different brands during this time, and this brand really stood out to me, with its pleasant taste, excellent cleaning, and great mouth feel. In all fairness, there are many other great brands available, which are also very good. Since finding this new type of toothpaste, I have to question why it is not available mainstream in the US, and advertised. My dentist asked me if I was using a teeth whitening product, and didn’t seem very welcoming, when I shared what I was using. This product, cleans, whitens, and works to prevent teeth sensitivity. Excellent product.

### ⭐⭐⭐⭐⭐ Review
*by お***う on 24 November 2025*

アマゾンはいつも安くて助かっています。こちらを使い始めてからほんとにステインがつかなくなりました。歯と歯の間に少しついてしまうけど、ホワイトニングにそこまでこだわっていないので歯科検診時に取ってもらうことで良しとしています。 これまで知覚過敏対策の歯磨き粉ばかり使っていたけど、だんだん落ち着いてきたので今は専らアパガードです。プレミアムも買ってしまいました！

### ⭐⭐⭐⭐⭐ Review
*by C***A on 15 June 2025*

This product produced visible results within days of starting it. I dislike going to the dentist and was dealing with sensitivity from receding gums due to age. I was hoping to stop the recession as well as the sensitivity. Within days I noticed my teeth were cleaner of tartar; much whiter and a reduction in sensitivity. Plus this toothpaste, unlike many others, leaves your mouth with an wonderful clean feeling. The mint taste is good, fresh and light and lasts a long time after brushing. I haven't yet noticed any change in my gum recession, but I hope given time it will stop it. I love that it doesn't contain any fluoride. Yes, it's a bit expensive but worth it in my opinion. You don't need to use much to get results. I brush more than 4 times a day. I highly recommend this.

## Frequently Bought Together

- APAGARD® PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2
- Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Refresh Mint Flavor, 4 Fl Oz 1Pk
- Apagard Tooth Polish Royal 135g toothpaste, Direct from Japan

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*Product available on Desertcart Panama*
*Store origin: PA*
*Last updated: 2026-02-25*