When adding new fish or changing water do I have to use the entire 5ml/10gallon rule ?

I would do it if it were me. Most fish come from pet stores that are severly overstocked and under maintained so they are already stressed when you bring them home. Add to that the fact that they are being moved for the umpteeth time and they can use all the help they can get. I will say that I do use half doses when I move my fish from one tank to another only because they tanks are well maintained and the water parameters are pretty much the same so the fish are less stressed. Other people may have different opinions but this is my process and it works for me. I have four tanks. I have a 125, 90, 55 and a 40. I have been in the hobby for over 15 years. I also keep two aquatic turtles as well. Hope this helps.

any views on this product versus API's stresscoat?

Different products, API is a water conditioner, stressguard is an antiseptic for open wounds, cuts. I used StressGuard occasionally and API on water changes.

Do you have to remove purigen from your filter

No. Generally Seachem products are safe to use with other Seachem products. Normal filters, nor purigen filters have to be removed when using Stress Guard. It's perfectly safe.

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Seachem - Seachem StressGuard 500ml

4.8/5

Product ID: 725576558

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Details

Brand
seachem
Liquid Volume
500
Item Weight
1.15 Pounds
Item Form
Liquid
Target Species
Fish

💧500ml liquid formula

🧪Scientifically formulated stress relief

♻️Safe for all aquatic environments

Description

🐠 Keep your aquatic friends thriving—stress-free and stunning!

BOOSTS IMMUNITY - Helps fish recover from stress-induced vulnerability
EASY APPLICATION - Liquid form ensures hassle-free dosing every time
NATURAL INGREDIENTS - Supports fish health without harmful chemicals
INSTANT STRESS RELIEF - Calms fish quickly during transport or tank changes
UNIVERSAL COMPATIBILITY - Safe for freshwater and marine aquariums alike

Seachem StressGuard is a 500ml liquid solution designed to reduce stress in fish during transport, acclimation, or environmental changes. Safe for both freshwater and marine tanks, it uses natural ingredients to support fish health and immunity without harmful additives.

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TrustScore 4.5 | 7,300+ reviews

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Excellent communication throughout the order process. Product is perfect.

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Seachem - Seachem StressGuard 500ml

Details

Description

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Common Questions

Item model number	523
Is Discontinued By Manufacturer	No
Item Form	Liquid
batteries required	No
Batteries Included	No